IFT46 Polyclonal Antibody-BS65787

IFT46 Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65787-50, BS65787-100

Swiss-Prot: Q9NQC8

Host: Rabbit

IFT46 Polyclonal Antibody-BS65787

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human,

Applications: WB,

All Applications: WB=1:500-2000

Background: IFT46 is a 304 amino acid protein that belongs to the IFT46 family. IFT46 localizes to the cilium basal body but can also be found along the length of the cilium and is a part of a complex involved in intraflagellar transport (IFT). In addition, IFT46 is involved in the bi-directional movement of particles that is required for the assembly, maintenance, and functionality of primary cilia. Furthermore, IFT46 may be involved in skeletogenesis and chondrocyte maturation. Two isoforms exist due to alternate splicing events and the gene encoding IFT46 maps to human chromosome 11. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Purification and Purity: affinity purified by Protein A

Specificity: IFT46 Polyclonal Antibody detects endogenous levels of IFT46 protein.

Bioworld Molecular Weight: 34 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti-IFT46 at 1/1000 dilution, Primary: Anti- IFT46 at 1/1000 dilution

Alternative Name: C11orf2; C11orf60; IFT46; IFT46_HUMAN; Intraflagellar transport protein 46 homolog.聽聽

Immunogen: KLH conjugated synthetic peptide derived from human IFT46:101-200/304

Modification: Unmodified

Conjugate: Unconjugated