Product Description

IFT88 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: AP6022-50, AP6022-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: IFT88 (Intraflagellar transport protein 88), also known as TG737 or TTC10 (TPR repeat protein 10), is an 833 amino acid protein that contains 12 TPR repeats and belongs to the TPR family. Expressed in lung, heart, liver, brain, pancreas, kidney and skeletal muscle, IFT88 is thought to interact with other intraflagellar transport proteins and may play a role in the assembly and maintenance of the vertebrate outer segment. Additionally, IFT88 is thought to function as a centrosomal protein that may regμlate the G1 to S phase cell cycle transition in non-ciliated cells. Defects in the gene encoding IFT88 may be associated with the pathogenesis of polycystic kidney disease, a genetic disorder that is characterized by the presence of cysts within the kidneys. IFT88 expression is downregμlated in hepatocellμlar carcinomas, suggesting a role for IFT88 in tumor suppression. Mμltiple isoforms of IFT88 exist due to alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10, TPR repeat protein 10, TG737, TTC10

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human IFT88.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IFT88 polyclonal antibody detects endogenous levels of IFT88 protein.

Molecular Weight: ~ 94 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13099

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only