Product Description

IgA Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26179-50, RA26179-100

Citations, Manuals and MSDS Available upon request.

Background: disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t (1;14) (q21;q32) that forms a FCRL4-IGHA1 fusion protein.,function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.,PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Monomeric or polymeric.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 3493/3494

Protein MW (KDa): 38

SWISS: P01876/P01877

Source: Rabbit

Research Use Only