IgA rabbit pAb - ES2594

IgA rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2594-50, ES2594-100

Citations, Manuals and MSDS Available upon request.

Background: disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t (1; 14) (q21; q32) that forms a FCRL4-IGHA1 fusion protein., function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system., PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352., similarity:Contains 3 Ig-like (immunoglobulin-like) domains., subunit:Monomeric or polymeric.,

Alternate Name: IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human IgA. AA range:227-276

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 38kD

Human Gene ID: 3493/3494

Human SWISS Prot NO: P01876/P01877

Subcellular Location: Secreted. Cell membrane.

Research Use Only