IGF-I Receptor β (phospho-Tyr1135) Rabbit Polyclonal Antibody - RA26194

IGF-I Receptor β (phospho-Tyr1135) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26194-50, RA26194-100

Citations, Manuals and MSDS Available upon request.

Background: insulin like growth factor 1 receptor (IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 3480

Protein MW (KDa): 155

SWISS: P08069

Source: Rabbit

Research Use Only