Product Description

IGF-IR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11495-50, RA11495-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: insulin like growth factor 1 receptor (IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

Reactivity: Human

Host: Mouse

Applications: WB, IHC-p, IF(paraffin section), ELISA

Alternate Names: IGF1R, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor, CD antigen CD221

Clonality: Monoclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Human Gene ID: 3480

Research Use Only