IGF1R Monoclonal Antibody - BT-MCA4754

IGF1R Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4754-50, BT-MCA4754-100

Citations, Manuals and MSDS Available upon request.

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research Areas: Others

Target Protein: IGF1R

Applications: WB, FCM

Clonality: Monoclonal

Clone ID: 3B4E3

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: IGF1R

Immunogen: Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 154.8kDa

UniProt Accession: P08069

Synonyms: IGFR, CD221, IGFIR, JTK13

GeneID: 3480

Research Use Only