IGF2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90688-50, BS90688-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P01344(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, ICC/IF, IHC
All Applications: WB:1:1,000
ICC:1:100-1:500
IHC:1:50-1:200
Background: IGF-II (Insulin-like growth factor II; also multiplication-stimulating polypeptide/MSP and somatomedin-A) is a secreted 8 kDa polypeptide that belongs to the insulin family of peptide growth factors. It is part of a complex system of growth and metabolic-regulating proteins that is particularly important during development. It has been associated with nervous system proliferation and differentiation, myelination, adrenal cortical proliferation, and skeletal growth and differentiation. In human, IGF-II is primarily synthesized by the liver, and circulates at high levels in both fetus and adult. In rodent, however, IGF-II levels drop after the perinatal period, an effect attributed to the lack of a key gene promoter. This may indicate that postnatally, IGF-II has either a limited, or local effect only in rodent.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: IGF2 polyclonal antibody detects endogenous levels of IGF2 protein.
Bioworld Molecular Weight: 11 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of IGF2 on human placenta lysates using anti-IGF2 antibody at 1/1,000 dilution., ICC staining IGF2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: IGF-II, C11orf43, IGF 2, IGF II, IGF-II, IGF2, IGF2, IGFII, INSIGF, insulin like growth factor 2 (somatomedin A), Insulin like Growth Factor 2, Insulin like growth factor II, Insulin like growth factor II precursor, Insulin like growth factor type 2, pp9974, Preptin, putative insulin like growth factor II associated protein, Somatomedin A, Somatomedin-A,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified