Product Description

IgG1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3451-50, BS3451-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: IgG is a monomeric immunoglobμlin, built of two heavy chains gamma and two light chains. Each molecμle has two antigen binding sites. This is the most abundant immunoglobμlin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobμlins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC

Alternate Names: Ig gamma 1 chain C region, IGHG1, Immunoglobμlin Gm1,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IgG1.

Dilution: WB, 1:500 - 1:1000 IHC, 1:100 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1 polyclonal antibody detects endogenous levels of IgG1 protein.

Molecular Weight: ~ 41 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01857

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only