Product Description

IgM Chain C Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26209-50, RA26209-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: immunoglobulin heavy constant mu (IGHM) Homo sapiens Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which d

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: Ig mu chain C region

Clonality: Polyclonal

Dilution: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight: 50

Protein Molecular Weight (kDa): 50

Storage: -20°C/1 year

Human SwissProt Number: P01871

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only