IgM Chain C Polyclonal Antibody - RA26209

IgM Chain C Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26209-50, RA26209-100

Citations, Manuals and MSDS Available upon request.

Background: immunoglobulin heavy constant mu (IGHM) Homo sapiens Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910) . The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which d

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000

Alternative Names: Ig mu chain C region

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

Protein MW (KDa): 50

SWISS: P01871

Source: Rabbit

Research Use Only