Product Description

Ikaros 3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26218-50, RA26218-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: IKAROS family zinc finger 3 (IKZF3) Homo sapiens This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: IKZF3, ZNFN1A3, Zinc finger protein Aiolos, Ikaros family zinc finger protein 3

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight: 62

Protein Molecular Weight (kDa): 62

Storage: -20°C/1 year

Human Gene ID: 22806

Human SwissProt Number: Q9UKT9

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only