Ikaros 3 rabbit pAb - ES2599

Ikaros 3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2599-50, ES2599-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012],

Alternate Name: IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human IKZF3. AA range:361-410

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 62kD

Human Gene ID: 22806

Human SWISS Prot NO: Q9UKT9

Subcellular Location: Nucleus. Cytoplasm.; [Isoform 1]: Nucleus.; [Isoform 3]: Nucleus.; [Isoform 11]: Nucleus.; [Isoform 14]: Nucleus. Cytoplasm.; [Isoform 12]: Cytoplasm.

Research Use Only