Product Description

Ikaros (C-term) Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA10541-50, RA10541-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: IKAROS family zinc finger 1 (IKZF1) Homo sapiens This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding

Reactivity: Human

Host: Mouse

Applications: WB, IP

Alternate Names: CLL associated antigen KW 6, DNA-binding protein Ikaros, hIk 1, hIk-1, Hs.54452, IK1, Ikaros (zinc finger protein), IKAROS, IKAROS family zinc finger 1 (Ikaros), Ikaros family zinc finger protein 1, Ikzf1, IKZF1_HUMAN, LYF1, Lymphoid transcription factor LyF-1, PRO0758, Zinc finger protein subfamily 1A 1 (Ikaros), zinc finger protein subfamily 1A 1, Zinc finger protein, subfamily 1A, member 1, ZNFN1A1.

Clonality: Monoclonal

Dilution: wb 1:1000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 10320

Protein Molecular Weight（KDa): 58

Molecular Weight: 58

Research Use Only