IkB α Rabbit pAb - EA339

IkB α Rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: EA339-50, EA339-100

Citations, Manuals and MSDS Available upon request.

Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.

Alternate Name: I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody

Source: Rabbit

Applications: WB, IHC

Dilution: WB 1:500-1, 000  IHC 1:100-200

Reactivity: Human, Mouse, Rat

Immunogen: Recombinant Protein

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Polyclonal

Isotype: IgG

Concentration: 1mg/mL

Observed Band (KD): 40kDa

Human Gene ID: 4792

Human SWISS Prot NO: P25963

Subcellular Location: Cytoplasm,  Nucleus

Research Use Only