Product Description

IKB alpha Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63487-60, E-AB-63487-120, E-AB-63487-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: IKB alpha

Target Synonym: IKBA; MAD-3; NFKBI; IKB alpha; NFKBIA; EDAID2

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signaling transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P25963

Background: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human IKB alpha (NP_065390.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200 IF 1:20-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only