Product Description

IKK alpha/beta Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16443-50, BZ16443-100

Swiss-Prot: O15111/O14920

Host: Rabbit

IKK alpha/beta Polyclonal Antibody-BZ16443

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: IKK-beta a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 85 kDa; Observed MW: 85 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of IKK alpha/beta in HepG2Lysates using IKK alpha/beta antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using IKKalpha/beta antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample withBlocking peptide on the right.

Alternative Name: CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B

Immunogen: The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta. AA range:141-190

Modification: Unmodified

Conjugate: Unconjugated