IL-10 Polyclonal Antibody - BT-AP15815

IL-10 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15815-20, BT-AP15815-50, BT-AP15815-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Research Areas: Others

Target Protein: IL-10

Applications: WB, IHC, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: IL-10

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IL10. AA range:71-120

Storage: -20°C for one year

Concentration: 1 mg/ml

Molecular Weight (Da): 20kD

Synonyms: IL10, Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF

GeneID: 3586

Research Use Only