IL-17Rα Polyclonal Antibody - RA26275

IL-17Rα Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26275-50, RA26275-100

Citations, Manuals and MSDS Available upon request.

Background: interleukin 17 receptor A (IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: IL17RA; IL17R; Interleukin-17 receptor A; IL-17 receptor A; IL-17RA; CDw217; CD antigen CD217

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 23765

Protein MW (KDa): 90

SWISS: Q96F46

Source: Rabbit

Research Use Only