Product Description

IL-17Rα Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26276-50, RA26276-100

Citations, Manuals and MSDS Available upon request.

Background: interleukin 17 receptor A (IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, WB 1:500-2000

Alternative Names: Interleukin-17 receptor A (IL-17 receptor A;IL-17RA;CDw217;CD antigen CD217)

Applications: IHC-p; IF (paraffin section) ; WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 23765

Protein MW (KDa): 90

SWISS: Q96F46

Source: Rabbit

Research Use Only