IL-17RC Polyclonal Antibody - RA26274

IL-17RC Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26274-50, RA26274-100

Citations, Manuals and MSDS Available upon request.

Background: interleukin 17 receptor C (IL17RC) Homo sapiens This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA) . Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: IL17RC; Interleukin-17 receptor C; IL-17 receptor C; IL-17RC; Interleukin-17 receptor homolog; IL17Rhom; Interleukin-17 receptor-like protein; IL-17RL; ZcytoR14

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 84818

Protein MW (KDa): 70

SWISS: Q8NAC3

Source: Rabbit

Research Use Only