IL-26 Rabbit Monoclonal Antibody-MB66439

IL-26 Rabbit Monoclonal Antibody

Product: Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Catalogue Numbers: MB66439-50, MB66439-100

Sizes: 50µl, 100µl

Swiss-Prot: Q9NPH9

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IP

Background: May play a role in local mechanisms of mucosal immunity and seems to have a pro-inflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.

Product: Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of IL-26 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of IL-26 expression in Hela (A), A549 (B), HL60 (C), U251 (D) whole cell lysates., Immunohistochemical analysis of IL-26 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.128). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Bioworld Molecular Weight: ~ 20 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: AK155; Interleukin-26; IL-26; Protein AK155

Immunogen: A synthetic peptide of human IL-26

Conjugate: Unconjugated

Modification: Unmodified