IL-27A Polyclonal Antibody - BT-AP10318

IL-27A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10318-20, BT-AP10318-50, BT-AP10318-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Research Areas: Immunology; Cell biology

Target Protein: IL27

Applications: IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Interleukin-27 subunit alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8NEV9; Mouse: Q8K3I6

Synonyms: Interleukin-27 subunit alpha;IL-27 subunit alpha;IL-27-A;IL27-A;p28; Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28

GeneID: Human: 246778; Mouse: 246779

Research Use Only