IL-2Rα (R264) Polyclonal Antibody-BS1758

IL-2Rα (R264) Polyclonal Antibody

Catalogue Numbers: BS1758-50, BS1758-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01589

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:500~1:1000
IF: 1:50~1:200

Background: The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IL-2Rα (R264) polyclonal antibody detects endogenous levels of IL-2Rα protein.

Extra Notes: Western blot (WB) analysis of IL-2Rα (R264) polyclonal antibody at 1:500 dilution
Lane1:PC3 whole cell lysate(40ug)
Lane2:A549 whole cell lysate(40ug)
Lane3:PMVEC whole cell lysate(40ug)
Lane4:BV2 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25; IL2RA

Immunogen: Synthetic peptide, corresponding to amino acids 231-280 of Human IL-2Rα.

Conjugate: Unconjugated

Modification: Unmodified