IL-4 rabbit pAb - ES5878

IL-4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5878-50, ES5878-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Alternate Name: IL4; Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

Source: Rabbit

Applications: WB; Flow Cyt; ELISA

Dilution: WB 1:500-2000; Flow Cyt 1:50-200; ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from the C-terminal region of human IL-4.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 18kD

Human Gene ID: 3565

Human SWISS Prot NO: P05112

Subcellular Location: Secreted

Research Use Only