Product Description

IL-4 Rat Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65855-50, MB65855-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Interleukin-4 (IL-4) is a cytokine secreted by activated T cells, basophils, and mast cells. While it contributes to many immunomodμlatory responses, it is mainly recognized as the cytokine responsible for eliciting differentiation of naive T cells into Th2 lineage cells that are defined by their secretion of IL-4, IL-5, and IL-10. In addition, IL-4 contributes to immunoglobμlin class switching by inducing the production of IgE from B cells. IL-4 acts through the IL-4 receptor, leading to tyrosine phosphorylation and activation of the Stat6 transcription factor.

Category: Primary Antibody

Reactivity: Human

Host: Rat

Applications: IF, FC

Alternate Names: Interleukin-4, IL-4, B-cell stimμlatory factor 1, BSF-1, Binetrakin, Lymphocyte stimμlatory factor 1, Pitrakinra

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: CHO-expressed recombinant human IL-4

Dilution: IF (1/50 - 1/200)

Purification: The monoclonal antibody was affinity-purified from Rat antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes human IL-4

Molecular Weight: ~ 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P05112

Product: Rat IgG1 kappa. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Research Use Only