IL-4 Rat Monoclonal Antibody-MB65855

IL-4 Rat Monoclonal Antibody

Catalogue Numbers:MB65855-50, MB65855-100

Product: Rat IgG1 kappa. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Swiss-Prot: P05112

Host: Rat

Reactivity: Human

Applications: IF, FC

All Applications: IF (1/50 - 1/200)

Background: Interleukin-4 (IL-4) is a cytokine secreted by activated T cells, basophils, and mast cells. While it contributes to many immunomodulatory responses, it is mainly recognized as the cytokine responsible for eliciting differentiation of naive T cells into Th2 lineage cells that are defined by their secretion of IL-4, IL-5, and IL-10. In addition, IL-4 contributes to immunoglobulin class switching by inducing the production of IgE from B cells. IL-4 acts through the IL-4 receptor, leading to tyrosine phosphorylation and activation of the Stat6 transcription factor.

Purification and Purity: The monoclonal antibody was affinity-purified from Rat antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 17 kDa

Specificity: Recognizes human IL-4

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

Immunogen: CHO-expressed recombinant human IL-4

Conjugate: Unconjugated

Modification: Unmodified