Product Description

IL-4R/CD124 (Phospho-Y497) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: AP0132-50, AP0132-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The armadillo (ARM) repeat family of proteins are related to the Drosophilamelanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cellmigration, cell proliferation, tissue maintenance and tumorigenesis. They areintracellμlar proteins and function in signal transduction and cell structure. ARMCX3 (armadillo repeat containing, X-linked 3), also known as ALEX3(ARM protein lost in epithelial cancers on chromosome X 3), is a single passmembrane protein belonging to the armadillo repeat family of proteins.ARMCX3 contains three ARM repeats and shares 60% sequence similaritywith the related proteins, ARMCX1 and ARMCX2. ARMCX3 is believed toplay a role in embryonic development and tissue maintenance and may alsofunction as a tumor suppressor.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD_antigen: CD124, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding protein, IL4-BP, IL4R, 582J2.1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human IL-4R/CD124 around the phosphorylation site of Tyrosine 497.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IL-4R/CD124(Phospho-Y497) polyclonal antibody detects endogenous levels of IL-4R/CD124 protein only when phosphorylated at Tyr497.

Molecular Weight: ~ 78 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P24394

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Research Use Only