Product Description

IL-6 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS6419-50, BS6419-100

Swiss-Prot: P05231

Host: Rabbit

IL-6 Polyclonal Antibody-BS6419

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the brea own of fats and to improve insulin resistance.Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IL-6 polyclonal antibody detects endogenous levels of IL-6 protein.

Bioworld Molecular Weight: ~ 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of IL-6 polyclonal antibody at 1:500 dilution
Lane 1: HCC827 whole cell lysate (40ug)
Lane 2: PC3 whole cell lysate (40ug, Immunohistochemistry (IHC) analysis of IL-6 pAb in paraffin-embedded Rat Lung tissue.

Alternative Name: Interleukin BSF 2;
B cell differentiation factor;
B cell stimulatory factor 2;
B-cell stimulatory factor 2;
BSF 2;
BSF-2;
BSF2;
CDF;
CTL differentiation factor;
Cytotoxic T cell differentiation factor;
Hepatocyte stimulating factor;
HGF;
HPGF;
HSF;
Hybridoma growth factor;
Hybridoma growth factor Interferon beta-2;
Hybridoma plasmacytoma growth factor;
IFN-beta-2;
IFNB2;
IL 6;
IL-6;
IL6;
IL6 protein;
IL6;
Interferon beta 2;
Interferon beta-2;
Interleukin 6 (interf

Immunogen: Recombinant full length Human IL-6.

Modification: Unmodified

Conjugate: Unconjugated