IL-9R (phospho Ser519) rabbit pAb - ES5889

IL-9R (phospho Ser519) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5889-50, ES5889-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: IL9R; Interleukin-9 receptor; IL-9 receptor; IL-9R; CD antigen CD129

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-9R around the phosphorylation site of Ser519. AA range:472-521

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 57kD

Human Gene ID: 3581

Human SWISS Prot NO: Q01113

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Secreted.

Research Use Only