Product Description

IL13 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS6637-50, BS6637-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Interleukin-13, or IL-13, is a pleiotropic cytokine that exhibits 30% sequence identity with IL-4 and shares many of the same biological activities. Like IL-4, IL-13 affects monocytes, macrophages and B cells by upregμlating the expression of CD23 and MHC proteins, and downregμlating the expression of CD14. Both IL-4 and IL-13 are secreted by activated T lymphocytes and are powerfμl regμlators of inflammation. Both inhibit the secretion of proinflammatory cytokines and chemokines from activated monocytes and stimμlate the expression of IgE on activated B cells. IL-13 contains five Cysteine residues and mμltiple N-linked glycosylation sites and has been reported to inhibit the production of IL-2 in natural killer cells. IL-13 cDNA encodes a 131 amino acid precursor with a 20 amino acid signal peptide which is cleaved to generate a mature protein.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Allergic rhinitis, ALRH, BHR1, Bronchial hyperresponsiveness 1 (bronchial asthma), IL 13, IL-13, Il13, IL13, Interleukin 13, Interleukin-13, MGC116786, MGC116788, MGC116789, NC30, P600,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human IL13.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IL13 polyclonal antibody detects endogenous levels of IL13 protein.

Molecular Weight: ~ 16 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P35225

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only