IL16 rabbit pAb - ES8610

IL16 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8610-50, ES8610-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

Alternate Name: Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)]

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthetic peptide from human protein at AA range: 900-960

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 67kD

Human Gene ID: 3603

Human SWISS Prot NO: Q14005

Subcellular Location: [Interleukin-16]: Secreted.; [Isoform 1]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.

Research Use Only