Product Description

IL17D Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60982-50, BS60982-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regμlatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. The proinflammatory cytokine Interleukin 17D (IL-17D), also known as IL-27, is the largest member of the IL-17 family of cytokines. It is produced by CD4+ T cells and is predominantly expressed in brain, lung, heart, adipose tissue, pancreas and skeletal muscle. IL-17D regμlates the production of other cytokines in endothelial cells, including IL-6, IL-8 and GM-CSF. It may play a role in the activation of the endothelium, which is the site of attachment for migrating immune cells. In addition, IL-17D may play a role in the amplification of a local immune response.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Interleukin-17D, IL-17D, Interleukin-27, IL-27, IL17D, IL27

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human IL17D.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IL17D polyclonal antibody detects endogenous levels of IL17D protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8TAD2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only