Product Description

IL1R2 Polyclonal Antibody

Catalogue Numbers: BS62076-50, BS62076-100

Sizes: 50µl, 100µl

Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.

Swiss-Prot: P27930

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Non-signaling receptor for IL1A, IL1B and IL1RN. ReducesIL1B activities. Serves as a decoy receptor by competetive bindingto IL1B and preventing its binding to IL1R1. Also modulatescellular response through non-signaling association with IL1RAPafter binding to IL1B. IL1R2 (membrane and secreted forms)preferentially binds IL1B and poorly IL1A and IL1RN. The secretedIL1R2 recruits secreted IL1RAP with high affinity; this complexformation may be the dominant mechanism for neutralization of IL1Bby secreted/soluble receptors.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IL1R2 polyclonal antibody detects endogenous levels of IL1R2 protein.

Extra Notes: Western blot (WB) analysis of IL1R2 polyclonal antibody at 1:500 dilution
Lane1:Jurkat whole cell lysate(20µg)
Lane2:HEK293T whole cell lysate(40µg)
Lane3:The Kidney tissue lysate of Rat(40ug)
Lane4:The Heart tissue lysate of Mouse(40ug)

Bioworld Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b; mIL-1R2; mIL-1RII;
sIL-1R2; sIL-1RII; IL1R2; IL1RB

Immunogen: Synthetic peptide, corresponding to Human IL1R2

Conjugate: Unconjugated

Modification: Unmodified