Product Description

IL1RA Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26287-50, RA26287-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: disease:Genetic variation in IL1RN is associated with susceptibility to diabetic nephropathy [MIM:612628]; also called susceptibility to microvascular complications of diabetes type 4 (MVCD4). Diabetic nephropathy is a kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney. Features include increased urine protein and declining kidney function., function:Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity., online information:Interleukin-1 entry, online information:The Singapore human mutation and polymorphism database, pharmaceutical:Available under the name Kineret (Amgen). Used for the reduction in signs and symptoms and slowing the progression of structural damage in moderately to severely active rheumatoid arthritis., similarity:Belongs to the IL-1 family., tissue specificity:The intracellular form of IL1RN is predominantly expressed in epithelial cells.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Interleukin-1 receptor antagonist protein (IL-1RN;IL-1ra;IRAP;ICIL-1RA;IL1 inhibitor;Anakinra)

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Storage: -20°C/1 year

Human Gene ID: 3557

Human SwissProt Number: P18510

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only