Product Description

IL21R Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32789-50, RA32789-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: interleukin 21 receptor (IL21R) Homo sapiens The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 59

Protein Molecular Weight (kDa): 59

Storage: -20°C/1 year

Human Gene ID: 50615

Human SwissProt Number: Q9HBE5

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only