Product Description

IL36RN Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60972-50, BS60972-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: IL-1 (Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors, NFκB and AP-1, thereby promoting host response to injury or infection. The IL-1 superfamily is comprised of several ligands and receptors. IL-1F5, also known as IL-1δ, IL-1 like protein 1 (IL-1L1), IL-1HY1, IL-1ra (receptor antagonist) homolog 1 or IL-1 related protein 3 (IL-1rp3), is a secreted ligand belonging to this superfamily. IL-1F5 is expressed in monocytes and macrophages and is activated by endotoxins. It shares 47% sequence identity with IL-1ra and similarly lacks the loop between the fourth and fifth ∫-strands. IL-1F5 acts as an antagonist, inhibiting the IL-1F9 activation of NFκB. Similar to other family members, IL-1F5 can be regμlated by bacterial lipopolysaccharide (LPS).

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB

Alternate Names: Interleukin-36 receptor antagonist protein, FIL1 delta, IL-1-related protein 3, IL-1RP3, Interleukin-1 HY1, IL-1HY1, Interleukin-1 delta, IL-1 delta, Interleukin-1 family member 5, IL-1F5, Interleukin-1 receptor antagonist homolog 1, Interleukin-1 receptor antagonist homolog 1, Interleukin-1-like protein 1, IL-1L1, IL36RN, FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human IL36RN.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IL36RN polyclonal antibody detects endogenous levels of IL36RN protein.

Molecular Weight: ~ 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UBH0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only