Product Description

IL36RN Polyclonal Antibody

Catalogue Numbers: BS60972-50, BS60972-100

Sizes: 50µl, 100µl

Alternative Name: Interleukin-36 receptor antagonist protein; FIL1 delta; IL-1-related protein 3; IL-1RP3; Interleukin-1 HY1; IL-1HY1; Interleukin-1 delta; IL-1 delta; Interleukin-1 family member 5; IL-1F5; Interleukin-1 receptor antagonist homolog 1; Interleukin-1 receptor antagonist homolog 1; Interleukin-1-like protein 1; IL-1L1; IL36RN; FIL1D; IL1F5; IL1HY1; IL1L1; IL1RP3

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UBH0

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: IL-1 (Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors, NFκB and AP-1, thereby promoting host response to injury or infection. The IL-1 superfamily is comprised of several ligands and receptors. IL-1F5, also known as IL-1δ, IL-1 like protein 1 (IL-1L1), IL-1HY1, IL-1ra (receptor antagonist) homolog 1 or IL-1 related protein 3 (IL-1rp3), is a secreted ligand belonging to this superfamily. IL-1F5 is expressed in monocytes and macrophages and is activated by endotoxins. It shares 47% sequence identity with IL-1ra and similarly lacks the loop between the fourth and fifth ∫-strands. IL-1F5 acts as an antagonist, inhibiting the IL-1F9 activation of NFκB. Similar to other family members, IL-1F5 can be regulated by bacterial lipopolysaccharide (LPS).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IL36RN polyclonal antibody detects endogenous levels of IL36RN protein.

Bioworld Molecular Weight: ~ 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of IL36RN polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: H9C2 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human IL36RN.

Conjugate: Unconjugated

Modification: Unmodified