Product Description

IL5RA Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16515-60, E-AB-16515-120, E-AB-16515-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: IL5RA

Target Synonym: CD125; CD125 antigen; CDw125; HSIL5R3; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; IL5R; IL5RA; IL5RA; Interleukin 5 Receptor alpha; Interleukin 5 Receptor alpha chain; Interleukin 5 receptor alpha subunit; Interleukin 5 receptor subunit alpha; Interleukin 5 receptor type 3; Interleukin-5 receptor subunit alpha; MGC26560

Research Areas: Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q01344

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human IL5RA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Calculated MW: 48kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only