ILF2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90710-50, BS90710-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q12905(Human) Q9CXY6(Mouse) Q7TP98(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IP, IHC FC
All Applications: WB:1:500
IHC:1:50-1:200
FC:1:50-1:100
IP:1:10-1:20
Background: NF45 (ILF2, nuclear factor of activated T cells 45 kDa) is a transcription factor that interacts with NF90 (ILF3, DRBP76) to regulate gene expression. NF45 and NF90 are proteins that belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. The NF45/NF90 heterodimer is mainly involved in regulating IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES).
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: ILF2 polyclonal antibody detects endogenous levels of ILF2 protein.
Bioworld Molecular Weight: 43 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of ILF2 on different cell lysates using anti-ILF2 antibody at 1/500 dilution.
Positive control:
Lane 1: Mouse testis tissue
Lane 2: HL-60
Lane 3: SH-SY-5Y, Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-ILF2 antibody. Counter stained with hematoxylin.
Alternative Name: ILF2, NF45, PRO3063, HGNC:6037, ILF 2, ilf2, ILF2, Interleukin enhancer binding factor 2, Interleukin enhancer binding factor 2, 45kDa, Interleukin enhancer-binding factor 2, MGC8391, NF 45, NF45, Nuclear factor of activated T cells 45 kDa, Nuclear factor of activated T-cells 45 kDa, PRO3063,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodified