Product Description

ILKAP (K71) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2359-50, BS2359-100

Sizes: 50µl, 100µl

Swiss-Prot: Q9H0C8

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

Background: ILKAP (integrin-linked kinase-associated serine/threonine phosphatase 2C),also known as PP2Cδ, is a 392 amino acid cytoplasmic protein phosphatase
that selectively interacts with integrin linked kinase (ILK) to regulate growth factor signaling and cell adhesion. While widely expressed, ILKAP is found at highest levels in striated muscle with lower levels found in smooth muscle.ILKAP belongs to the PP2C family and contains one PP2C-like domain. ILKAP has been suggested to inhibit oncogenic transformation and the ILK-GSK3βsignaling axis, and can bind two magnesium or manganese ions per subunit as cofactors. The gene encoding ILKAP maps to human chromosome 2,which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: he antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LKAP (K71)pAb detects endogenous levels of ILKAP protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ILKAP (K71) polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: sp2/0 whole cell lysate
Lane 3: H9C2 whole cell lysate, Immunohistochemistry (IHC) analyzes of ILKAP (K71) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Integrin-linked kinase-associated serine/threonine phosphatase 2C; ILKAP; ILKAP

Immunogen: Synthetic peptide, corresponding to amino acids 40-90 of Human ILKAP.

Conjugate: Unconjugated

Modification: Unmodified