Product Description

IMPDH2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90714-50, BS90714-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P12268(Human) P24547(Mouse) E9PU28(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC IF, IHC FC IP,

All Applications: WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200
FC:1:10-1:50
IP:1:10-1:50

Background: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: IMPDH2 polyclonal antibody detects endogenous levels of IMPDH2 protein.

Bioworld Molecular Weight: 56 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of IMPDH2 on Daudi cell lysate using anti-IMPDH2 antibody at 1/2,000 dilution., ICC staining IMPDH2 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: IMP dehydrogenase 2, IMPD 2, IMPDH 2, IMPDH2, IMPD2, IMDH2, IMP (inosine monophosphate) dehydrogenase 2, IMP dehydrogenase 2, IMP oxireductase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH-II, Impdh2, Inosine 5' monophosphate dehydrogenase 2, Inosine 5' phosphate dehydrogenase 2, Inosine monophosphate dehydrogenase type II, Inosine-5''-monophosphate dehydrogenase 2,

Immunogen: Recombinant protein within C-terminal human IMPDH2.

Conjugate: Unconjugated

Modification: Unmodified