INCENP (Phospho-Thr59) Rabbit Polyclonal Antibody - RA36870

INCENP (Phospho-Thr59) Rabbit Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA36870-50, RA36870-100 Citations, Manuals and MSDS Available upon request. Background: inner centromere protein (INCENP) Homo sapiens In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997) . The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142) . The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]) . These include CENPE (MIM 117143) ; MCAK (MIM 604538) ; KID (MIM 603213) ; cytoplasmic dynein (e.g., MIM 600112) ; CliPs (e.g., MIM 179838) ; and CENPF/mitosin (MIM 600236) . The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization alo Condition: Liquid in PBS containing 50% glycerol, and 0.186% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 Alternative Names: Inner centromere protein Applications: WB Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 3619 SWISS: Q9NQS7 Source: Rabbit Research Use Only