Product Description

ING3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32807-50, RA32807-100

Citations, Manuals and MSDS Available upon request.

Background: inhibitor of growth family member 3 (ING3) Homo sapiens The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 54556

Protein MW (KDa): 45

SWISS: Q9NXR8

Source: Rabbit

Research Use Only