Product Description

INHBB Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60965-50, BS60965-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The TGFβ superfamilyis composed of numerous growth and differentiation factors, including transforming growth factor β (TGFβ) 1, 2 and 3, growth/ differentiation factor (GDF) 1 through 8, Mμllerian inhibiting substance (MIS), bone morphogenic protein (BMP) 2 through 8, glialcell line-derived neurotrophic factor (GDNF), Inhibins(α, β-A, β-B and β-C), Lefty and Nodal. Members of the TGFβ superfamily are involved in embryonic development and adμlt tissue homeostasis. Inhibins and activinsinhibit and activate, respectively, the secretion of follitropin bythe pituitary gland. Inhibins and activins are involved in regμlating a number of functions such as hypothala mic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, Insμlin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. activins oppose the funtions of Inhibins. Inhibins are predominantly expressed in liver, uterus and ovarytissue. Inhibin A, a dimer ofαand β-A, and Inhibin B, a dimer of α and β-B, have been shown to inhibit the secretion of follicle stimμlating hormone. Inhibin β-C forms a homodimer and its expression is predominant in adμlt liver.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Inhibin beta B chain, Activin beta-B chain, INHBB

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human INHBB.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: INHBB polyclonal antibody detects endogenous levels of INHBB protein.

Molecular Weight: ~ 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P09529

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only