Inhibin β-C (V129) Polyclonal Antibody-BS3449

Inhibin β-C (V129) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3449-50, BS3449-100

Sizes: 50µl, 100µl

Swiss-Prot: P55103

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

Background: Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth depending on their subunit composition. Activins oppose the funtions of inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue, but also in benign prostatic hyperplasia. Inhibin A, a dimer of α and β-A, and inhibin B, a dimer of α and β-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin β-C forms a homodimer and its expression is predominant in adult liver and in benign prostatic hyperplasia.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Inhibin β-C (V129) polyclonal antibody detects endogenous levels of Inhibin β-C protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Inhibin β-C (V129) pAb in paraffin-embedded human liver carcinoma tissue at 1:50.showing strong cytoplasmic staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Molecular Weight: ~ 30 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Inhibin beta C chain; Activin beta-C chain; INHBC

Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human Inhibin β-C.

Conjugate: Unconjugated

Modification: Unmodified