INPP5J rabbit pAb - ES5542

INPP5J rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5542-50, ES5542-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:1D-myo-inositol 1, 3, 4, 5-tetrakisphosphate + H (2)O = 1D-myo-inositol 1, 3, 4-trisphosphate + phosphate., catalytic activity:D-myo-inositol 1, 4, 5-trisphosphate + H (2)O = myo-inositol 1, 4-bisphosphate + phosphate., domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein., function:Inositol 5-phosphatase, which converts inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate. Also converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate to inositol 1, 3, 4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles., PTM:Phosphorylated at Ser/Thr residues., similarity:Belongs to the inositol-1, 4, 5-trisphosphate 5-phosphatase type II family., subcellular location:Predominantly localized to membrane ruffles.,

Alternate Name: INPP5J; PIB5PA; PIPP; Phosphatidylinositol 4; 5-bisphosphate 5-phosphatase A; Inositol polyphosphate 5-phosphatase J

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat

Immunogen: Synthesized peptide derived from INPP5J . at AA range: 850-930

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 27124

Human SWISS Prot NO: Q15735

Subcellular Location: Cytoplasm. Predominantly localized to membrane ruffles.

Research Use Only