INSI2 Polyclonal Antibody - BT-AP10395

INSI2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10395-20, BT-AP10395-50, BT-AP10395-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Research Areas: Signal transduction; Cell biology;; Metabolism

Target Protein: INSIG2

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Insulin-induced gene 2 protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y5U4; Mouse: Q91WG1; Rat: Q80UA9

Synonyms: Insulin-induced gene 2 protein;INSIG-2

GeneID: Human: 51141

Research Use Only