INSRR Polyclonal Antibody-BS90716

INSRR Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90716-50, BS90716-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P14616(Human) Q9WTL4(Mouse) Q64716(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:500
IHC:1:50-1:200

Background: The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment.Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: INSRR polyclonal antibody detects endogenous levels of INSRR protein.

Bioworld Molecular Weight: 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Insulin Receptor R antibody. Counter stained with hematoxylin., Fig 2: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Insulin Receptor R antibody. Counter stained with hematoxylin.

Alternative Name: IRR, INSRR, INSRR, INSRR, Insulin receptor related receptor precursor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, insulin receptor-related receptor, IR R, IR related receptor, IR-related receptor, IRR, Sir r, Sirr,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified