Insulin Degrading Enzyme Monoclonal Antibody-MB12323

Insulin Degrading Enzyme Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12323-50, MB12323-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P14735

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 118 kDa; Observed MW: 118 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Insulin Degrading Enzyme/IDE in Hela, A549, HL-60, U2OS lysates using Insulin Degrading Enzyme antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Insulin Degrading Enzyme/IDE antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: INSULYSIN; Insulin degrading enzyme; IDE

Immunogen: A synthesized peptide derived from human IDE

Conjugate: Unconjugated

Modification: Unmodified