Insulin Mouse Monoclonal Antibody (PT0156) - RA12254

Insulin Mouse Monoclonal Antibody (PT0156) Size: 50μL, 100μL Catalogue Numbers: RA12254-50, RA12254-100 Citations, Manuals and MSDS Available upon request. Background: insulin (INS) Homo sapiens After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.26% sodium azide. Storage Instructions: -20°C/1 year Applications: IHC-p; IF (paraffin section) Species Cross-Reactivity: Human GeneID (Human): 3630 SWISS: P01308 Source: Mouse Research Use Only