Insulin Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA26379-50, RA26379-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: insulin (INS) Homo sapiens After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: IHC-p, IF (paraffin section), ELISA Alternate Names: Insulin [Cleaved into: Insulin B chain, Insulin A chain] Clonality: Polyclonal Dilution: IHC-p 1:50-200, ELISA 1:10000-20000 Storage: -20°C/1 year Human Gene ID: 3630 Human SwissProt Number: P01308 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only