Product Description

Insulin Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS9808M-50, BS9808M-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01308

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: ICC/IF, IHC

All Applications: IHC/ICC/IF: 1:50-1:200

Background: Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.

Purification and Purity: Protein A affinity purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of Insulin and does not cross-react with related proteins.

Bioworld Molecular Weight: ~ 12 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded rat pancreas tissue using anti-Insulin antibody. Counter stained with hematoxylin., Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-Insulin antibody. Counter stained with hematoxylin, Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Insulin antibody. Counter stained with hematoxylin.

Alternative Name: Insulin; INS

Immunogen: Recombinant antibody.

Conjugate: Unconjugated

Modification: Unmodified